A new study from Johns Hopkins adds further evidence that natural psilocybin use promotes positive long-term effects on well-being measures like emotion regulation, mental flexibility, and reduced neuroticism.
Published by the Johns Hopkins Center for Psychedelic and Consciousness Research, including authors like Roland Griffiths and Matthew Johnson, the study reviewed a sample of over 2,000 individuals intending to use psilocybin outside of clinical research settings.
- Data was collected 2 weeks before, the day before, 1-3 days after, 2-4 weeks after, and 2-3 months after psilocybin use.
- Results: A sample of 2,833 respondents. Participants were primarily college-educated men residing in the United States with a prior history of psychedelic use (mean age = 40 years).
- Participants primarily used dried psilocybin mushrooms (mean dose = 3.1 grams) for “self-exploration” purposes.
- Data collected before and after the psilocybin experience showed reductions in anxiety, depression, and alcohol misuse; increased cognitive flexibility, emotion regulation, spiritual wellbeing, and extraversion; and reduced neuroticism and burnout after psilocybin use.
- A small percentage of participants (11% at 2-4 weeks and 7% at 2-3 months) experienced persistent negative effects post-psilocybin, such as mood swings and depressive symptoms.
From the paper:
Results from this study, the largest prospective survey of naturalistic psilocybin use to date, support the potential for psilocybin to produce lasting improvements in mental health symptoms and general well-being.
For more like this, see our interview with Dr. Matthew Johnson:
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