Psilocybin
Silo Pharma to test a novel experimental intranasal formulation for PTSD
Silo’s SPC-15 was developed in collaboration with Columbia University
The post Silo Pharma to test a novel experimental intranasal formulation for PTSD…
The psychedelic manufacturer Silo Pharma, Inc. (Nasdaq: SILO) has started an exploratory feasibility study to evaluate the intranasal patented drug SPC-15 that works in serotonin receptors and is meant to reduce stress.
The company announced the study for the drug on Tuesday, which acts on the serotonin type 4 (5-HT4) receptor. Silo aims to have the Investigational New Drug (IND) submission to the Food and Drug Administration on target for the first quarter of next year.
The receptor plays an important role in regulating mood, anxiety and cognition. Drugs that activate this receptor have fast-acting antidepressant (AD)-like effects in preclinical models, according to a study by Nature. Drugs that act on it are known to be agents that act on serotonin receptors in the intestine and promote intestinal movement and emptying.
Silo’s SPC-15 was developed in collaboration with Columbia University and is meant to be used against stress and uses “biomarkers” for the treatment of stress-induced affective disorders, anxiety and PTSD.
Recent research in psychedelics such as psilocybin and LSD has shown that the substances act on the cortical 5-HT2A receptors.
Read more: Silo Pharma to develop ketamine implant for fibromyalgia and chronic pain
Read more: Silo Pharma prepares pre-IND package for FDA on novel ketamine formulation
“We believe our research partner’s patented proprietary nasal-to-brain technology could be well suited for the delivery of SPC-15, and we expect to receive the results of these in vitro lab tests by the end of September,” Silo Pharma CEO Eric Weisblum said.
“If the results are positive, we will work to prepare an Investigational New Drug (IND) application for submission to the FDA in the first quarter of 2024.”
Silo Pharma focuses on developing psychedelic medicines and research for people suffering from Post Traumatic Stress Disorder, Alzheimer’s disease and other rare neurological disorders.
The post Silo Pharma to test a novel experimental intranasal formulation for PTSD appeared first on Mugglehead Magazine.
psilocybin lsd ketamine psychedelic antidepressant anxiety ptsd serotonin psychedelics nasdaq silo pharma silo fda research-
Law & Regulation1 week ago
Clearmind signs agreement with Hebrew University for psychedelic compound rights
-
Psychedelics1 week ago
Cybin Announces Publication of Research Manuscript in the Journal of Medicinal Chemistry
-
Psilocybin1 week ago
California advances bill for psychedelics centers
-
Psilocybin4 days ago
Passover Perspectives: Psychedelics, Moses, and the Burning Bush
-
Psychedelics1 week ago
Psychedelics Can Offer More Than Therapy On Its Own
-
Psychedelics1 week ago
Revive Therapeutics Announces FDA Acceptance of Meeting Request for Long COVID Diagnostic Product
-
Psychedelics4 days ago
Algernon NeuroScience and the Centre for Human Drug Research to Present DMT Phase 1 Stroke Clinical Data at the Interdisciplinary Conference on Psychedelic Research June 6 – 8th, 2024
-
Psychedelics4 days ago
Revive Therapeutics Announces Type C Meeting Request Granted by FDA for Clinical Study of Bucillamine to Treat Long COVID