Psilocybin
Small Pharma gets approval for in-human injectable DMT trial
New phase I study will be held at MAC Clinical Research in Manchester, England next year
The post Small Pharma gets approval for in-human injectable DMT…
Biotechnology company, Small Pharma Inc. (TSXV: DMT) (OTCQB: DMTTF) has achieved an “exciting milestone” in its mission to progress drugs derived from dimethyltryptamine.
On Monday, the company announced that it had been granted approval from the Research Ethics Committee and U.K. Medicines and Healthcare products Regulatory Authority to begin a phase I trial with healthy participants examining the effects of SPL028, a patented injectable DMT drug.
Through the new study, the company will be investigating a short psychedelic experience lasting less than 30 minutes which is intended to offer convenience to patients. Psilocybin and LSD experiences for example can last anywhere between six and 12 hours.
Small Pharma has received approval from the MHRA and Research Ethics Committee to enter a Phase I first-in-human clinical trial with our proprietary deuterated candidate, SPL028. Full press release: https://t.co/51nT8PzaVn #mentalhealth #clinicaltrials #psychedelics pic.twitter.com/jqNcavaz9w
— Small Pharma (@SmallPharma) October 31, 2022
Read more: Small Pharma acquires U.S. patent for its DMT compounds
Read more: Spirit Plant Medicine Conference returns at UBC to discuss psychedelics and consciousness
The phase I study of SPL028 will be a “randomized, placebo-controlled, blinded, dose-escalating study” taking place at MAC Clinical Research in Manchester, England. The trial will be designed to assess the safety, tolerability, pharmacodynamics and pharmacokinetics of intravenous and intramuscular administration of SPL028.
The company expects to gain an improved understanding of the drug and its therapeutic potential through the trial, which is expected to commence before the end of June next year.
“This is an exciting milestone as we prepare to enter our first-in-human clinical trial with our proprietary deuterated candidate, SPL028. The goal is to deliver a treatment with a more extended psychedelic experience compared to our lead candidate, SPL026, which is around 20 minutes, but still significantly shorter than the psychedelic experiences of psilocybin or LSD, which are between six and 12 hours,” said Dr. Carol Routledge, chief scientific and medical officer of the company.
“We anticipate that the results of this phase I study will help us make a data-driven decision in selecting the dose and route of administration to take forward into potential future studies in patients.”
The post Small Pharma gets approval for in-human injectable DMT trial appeared first on Mugglehead Magazine.
psilocybin lsd dmt dimethyltryptamine psychedelic psychedelics small pharma research
-
Psychedelics7 days agoCybin Announces Grant of Additional U.S. Patent in Support of its CYB003 Breakthrough Therapy Program for Major Depressive Disorder
-
Psilocybin6 days agoAre Shrooms Legal in Oregon: Full Guide
-
Law & Regulation1 week agoNuminus reports declining revenue as the company restructures
-
Law & Regulation7 days agoGoing concern warnings cloud Xtacy Therapeutics’ shrunk losses
-
Psychedelics7 days agoOptimi Health Achieves Milestone: Completes In-House Production of MDMA Active Pharmaceutical Ingredient (API)
-
Psychedelics7 days agoPsyence Group’s NASDAQ Listed Associate, Psyence Biomedical Partners with Fluence and iNGENū CRO to Train Research Therapists for Phase IIb Psilocybin Trial
-
Psychedelics6 days agoAtai Life Sciences Announces the Publication of Beckley Psytech’s Phase 1 Study of BPL-003 in the Journal of Psychopharmacology
-
Law & Regulation5 days agoClearmind signs agreement with Hebrew University for psychedelic compound rights